Most Similar Movies to O Brother, Where Art Thou? (2000)
If you are looking for movies like O Brother, Where Art Thou? (2000), you might like movies tagged with keyword : adventure, comedy, crime, musical, drama, period piece, road movie, satire, great depression, quest, surreal, eccentric characters, political corruption, humor, stylized, ensemble cast, american south, fate, redemption, brotherhood .
The Grand Budapest Hotel (2014), The Sisters Brothers (2018), Lone Star State of Mind (2002), PK (2014), The Peanut Butter Falcon (2019), La tigre e la neve (2005), Three Kings (1999) ... Let's take a look at the following list...

The Grand Budapest Hotel (2014)
The adventures of Gustave H, a legendary concierge at a famous hotel from the fictional Republic of Zubrowka between the first and second World Wars, and Zero Moustafa, the lobby boy who becomes his most trusted friend.
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The Sisters Brothers (2018)
In 1850s Oregon, the infamous duo of assassins, Eli and Charlie Sisters, chase a gold prospector and his unexpected ally.
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Lone Star State of Mind (2002)
A young Texas mechanic (Jackson) tries to save a dim-witted relative from the mob. There's also something about the murderer of the mechanic's father, who's been in prison for 20 years, thanks to histestimony as a child.
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PK (2014)
An alien on Earth loses the only device he can use to communicate with his spaceship. His innocent nature and child-like questions force the country to evaluate the impact of religion on its people.
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The Peanut Butter Falcon (2019)
Zak runs away from his care home to make his dream of becoming a wrestler come true.
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La tigre e la neve (2005)
A love-struck Italian poet is stuck in Iraq at the onset of an American invasion.
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Three Kings (1999)
In the aftermath of the Persian Gulf War, four soldiers set out to steal gold that was stolen from Kuwait, but they discover people who desperately need their help.
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The Brothers Bloom (2008)
The Brothers Bloom are the best con men in the world, swindling millionaires with complex scenarios of lust and intrigue. Now they've decided to take on one last job - showing a beautiful and eccentric heiress the time of her life with a romantic adventure that takes them around the world.
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Cookie's Fortune (1999)
Conflict arises in the small town of Holly Springs when an old woman's death causes a variety of reactions among family and friends.
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Short Time (1990)
When a police detective thinks he is dying and learns that his life insurance pays out more if he dies in the line of duty, he tries to make that happen.
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Leaves of Grass (2009)
An Ivy League professor is lured back to his Oklahoma hometown, where his twin brother, a small-time pot grower, has concocted a scheme to take down a local drug lord.
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The Dukes of Hazzard: The Beginning (2007)
The Dukes, a Doo Wop group, were on top of the world at 17, and struggle for survival in 2008. Their manager is desperately trying to get them work but is met with failure at every turn. Finally pushed to the extreme , they pull a heist only a fool would attempt, which leaves them even more desperate. When all seems lost, they find themselves. Underneath the laughter,...Read all
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Singh Is Kinng (2008)
A comic caper about Happy Singh, a Punjabi villager who goes through a series of misadventures and eventually becomes the Kinng of the Australian underworld.
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Shoot the Piano Player (1960)
Gangsters stand in the way of a former concert pianist whose girlfriend has convinced him to make a comeback.
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More American Graffiti (1979)
College graduates deal with Vietnam and other issues of the late 1960s.
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Mojave Moon (1996)
Sexy, young Ellie picks up Al, 53, in a diner in LA to get a ride to her mom in the Mojave desert. Ellie leaves Al there with the pretty mom, her crazy, violent boyfriend and a body in his car trunk.
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Crimes and Misdemeanors (1989)
An ophthalmologist's mistress threatens to reveal their affair to his wife while a married documentary filmmaker is infatuated with another woman.
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Blinkende lygter (2000)
A gang of 4 Danish criminals are ordered by Færingen to steal a bag from a safe. When they see DKK4,000,000 in the bag, they keep it for themselves and head for Spain. They end up in a ruin of an old restaurant on Funen and renovate it.
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