Most Similar Movies to Muppets from Space (1999)
If you are looking for movies like Muppets from Space (1999), you might like movies tagged with keyword : gonzo, kermit the frog, fozzie bear, miss piggy, rat, government official, amusing, outer space, spaceship, house, earth, identity, alien landing, friendship, going home, invisibility, discovery, underdog, 1990s .
Lilo & Stitch (2002), Explorers (1985), The Gods Must Be Crazy II (1989), Muppet Treasure Island (1996), The SpongeBob SquarePants Movie (2004), Pete's Dragon (1977), Thunderbirds (2004) ... Let's take a look at the following list...

Lilo & Stitch (2002)
A Hawaiian girl adopts an unusual pet who is actually a notorious extra-terrestrial fugitive.
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Explorers (1985)
A boy obsessed with 50s sci-fi movies about aliens has a recurring dream about a blueprint of some kind, which he draws for his inventor friend. With the help of a third kid, they follow it and build themselves a spaceship. Now what?
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The Gods Must Be Crazy II (1989)
6 people comically meet in the Kalahari desert: a female NYC lawyer flying with a local zoologist/pilot in a mini-plane, a Cuban and an African soldier taking each other POW, a Boer elephant poacher and a bushman looking for his 2 sons.
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The SpongeBob SquarePants Movie (2004)
SpongeBob SquarePants takes leave from the town of Bikini Bottom in order to track down King Neptune's stolen crown.
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Pete's Dragon (1977)
An orphan boy and his magical dragon come to town with his abusive adoptive parents in pursuit.
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Thunderbirds (2004)
When The Hood finds and invades International Rescue's secret base and traps most of the Tracy family, only young Alan Tracy and his friends can save the day.
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The Cat in the Hat (2003)
Two bored children have their lives turned upside down when a talking cat comes to visit them.
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The Ant Bully (2006)
After Lucas Nickle floods an ant colony with his watergun, he's magically shrunken down to insect size and sentenced to hard labor in the ruins.
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Stuart Little 2 (2002)
Stuart and Snowbell set out across town to rescue a friend.
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The Secret of NIMH (1982)
To save her ill son, a field mouse must seek the aid of a colony of rats, with whom she has a deeper link than she ever suspected.
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Happy Feet Two (2011)
Mumble's son, Erik, is struggling to realize his talents in the Emperor Penguin world. Meanwhile, Mumble and his family and friends discover a new threat their home -- one that will take everyone working together to save them.
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Bedknobs and Broomsticks (1971)
An apprentice witch, three kids and a cynical magician conman search for the missing component to a magic spell to be used in the defense of Britain in WWII.
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DuckTales the Movie: Treasure of the Lost Lamp (1990)
Scrooge McDuck takes Huey, Dewey, and Louie to Egypt to find a pyramid and magic lamp.
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An American Tail: Fievel Goes West (1991)
A family of Emigre mice decide to move out to the west, unaware that they are falling into a trap perpetrated by a smooth talking cat.
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My Favorite Martian (1999)
A Martian lands on Earth and makes friends with a reporter.
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Quest for Camelot (1998)
An adventurous girl, a young blind hermit, and a goofy two-headed dragon race to find the lost sword Excalibur to save King Arthur and Camelot from disaster.
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The SpongeBob Movie: Sponge Out of Water (2015)
When a diabolical pirate above the sea steals the secret Krabby Patty formula, SpongeBob and his nemesis Plankton must team up in order to get it back.
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